This project aims to monitor the impact of human papillomavirus (HPV) vaccine on cervical cancer precursors and HPV types associated with those precursors.
Goals & Objectives
- Monitor HPV vaccine impact on cervical cancer precursors, cervical intraepithelial neoplasia (CIN) grade 2 and 3 and adenocarcinoma in situ (AIS).
- Monitor HPV vaccine impact on HPV types associated with CIN 2/3 and AIS lesions.
- Improve public health practice through local population-based surveillance of HPV-related cervical cancer precursors.
Statewide passive monitoring of CIN2/3 and AIS diagnoses from pathology laboratories
Population-based active surveillance for CIN 2/3 and AIS in New Haven county
enhanced data collection to determine HPV vaccination status specimen collection to determine HPV type associated with CIN2/3 and AIS diagnoses.
1. Linda M. Niccolai, Niti R. Mehta, James L. Hadler. Racial/Ethnic and poverty disparities in human papillomavirus vaccination completion. American Journal of Preventive Medicine. 2011;41(4):428-33.
2. DPH. Human Papillomavirus Types in Connecticut 2008-2009. Connecticut Epidemiologist 2011;31(6):25-26.
3. DPH. The Human Papillomavirus Vaccine Impact Monitoring Project (HPV-IMPACT) - Connecticut, 2008. Connecticut Epidemiologist 2010;30(2):5-6.
4. Susan Hariri, Elizabeth R. Unger, Suzanne E. Powell, Heidi M. Bauer, Nancy M. Bennett, Karen C. Bloch , Linda M. Niccolai, Sean Schafer, Lauri E. Markowitz, The HPV-IMPACT Working Group. The HPV vaccine impact monitoring project (HPV-IMPACT): assessing early evidence of vaccination impact on HPV-associated cervical cancer precursor lesions. Cancer Causes Control. 2011 Nov 23. [Epub ahead of print]
5. Niccolai LM, Russ C, Julian PJ, Hariri S, Sinard J, Meek JI, McBride V, Markowitz LE, Unger ER, Hadler JL and Sosa LE: Individual and geographic disparities in human papillomavirus types 16/18 in high-grade cervical lesions: Associations with race, ethnicity, and poverty. Cancer. 2013 Aug 15;119 (16) :3052-8. Epub 2013 May 9. PMID: 23661284
6. Niccolai LM, Julian PJ, Meek JI, McBride V, Hadler JL and Sosa LE: Declining rates of high-grade cervical lesions in young women in Connecticut, 2008-2011. Cancer Epidemiol Biomarkers Prev. 2013 Aug;22 (8) :1446-50. Epub 2013 May 23. PMID: 23704476
Article about the CT HPV-IMPACT project in the Fall 2011 issue of Yale Public Health: Tracking HPV.
Project Contact Person
Monica Brackney, MS
Connecticut Emerging Infections Program
One Church Street, 7th floor
New Haven, CT 06510