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In Memoriam: Dr. Fred Brown, An Expert on Foot-and-Mouth DiseaseDr. Fred Brown, Professor Adjunct at EPH from 1990 to 1995, died on February 20, 2004. Dr. Brown was born in 1925 in Burnley, Lancashire, England. He was educated at Manchester University, receiving his B.Sc. in 1944, his M.Sc. in 1946 and his Ph.D. in 1948. He spent nearly 30 years at the Animal Virus Research Institute's Pirbright laboratory in England. Following seven years as the Head of Virology Research and Development at Wellcome Biotechnology, he came to EPH in 1990 as an internationally recognized expert on the biochemistry, genetics, and taxonomy of picornaviruses, rhabdoviruses and caliciviruses. Dr. Brown's expertise was in foot-and-mouth disease virus (FMDV), the highly infectious virus which debilitates cattle, sheep, pigs, goats and deer. He made major contributions to the biochemical, molecular genetic, immunological and structural characterization of the disease. In 1989, his work resulting in the analysis of FMDV structure by x-ray crystallography was published. At Yale, Dr. Brown initiated a research program in the fine structure of viruses and a graduate program for the training of Ph.D. students in zoonotic diseases. He also collaborated with scientists at the U.S. government's Plum Island Foreign Animal Disease Center to conduct research on exotic diseases of cattle, sheep and other domestic animals. Dr. Brown was elected a Fellow of the Royal Society in 1981 and a Fellow of the Institute of Biology in 1986. He is survived by his wife, Audrey, and their two sons. |