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Makuch Assists in Development of Japanese Government's Initiative to Develop a Biostatistics Training Program

Robert Makuch, Ph.D. and Professor of Public Health in the Division of Biostatistics, is assisting in the development of a biostatistics training program in Japan, the first such program funded by the Japanese government. As part of this 5-year initiative, he was an invited presenter at the inaugural ceremony celebrating the opening of Kurume University School of Medicine’s Translational Research Center (TRC) where the first training program will reside.

In February 2003, Tatsuyuki Kakuma, who was a student in the Division of Biostatistics (’85 M.P.H., ’90 Ph.D.) and is now a Visiting Professor of Biostatistics at Kurume University and Professor of Biostatistics at the Japan Red Cross Kyushu International College of Nursing, approached Makuch about collaborating in the development of Kurume’s five year biostatistics training program. Plans for the program represented a major advance in Japan, where at the time, biostatistics barely existed as a discipline and there were no biostatistics training centers. Recognizing that the situation was hurting Japan’s ability to keep up with advances in drug development and diagnostic techniques resulting from the use of biostatistics in collaborations between doctors, statisticians and basic scientists, the Japanese government launched an initiative now housed at TRC.

Makuch, along with other leaders in the field, was invited to speak at the July 7, 2003 ceremony celebrating the opening of TRC, which was attended by more than 250 people. Makuch’s talk, entitled “Accomplishments and Challenges of Biostatistics in Medicine,” underscored the importance of biostatistical science to medical research. He stated that the “goals of translational medical research include the identification of new treatments that are highly efficacious, while at the same time insuring that these treatments have desirable safety profiles. A third goal is to achieve these first two aims in a way that is cost effective and time efficient.” Makuch also summarized recent advances in biostatistics/statistical genomics that play key roles in the analysis and objective identification of lead compounds and in the process of differentiation of compounds, and emphasized the contributions of the field of biostatistics to both preclinical drug development and the conduct of clinical studies.

Makuch says that the program, which will begin to train its first class of approximately 25 students this April, will “bring proteomics to the bedside” and hopefully lead to new treatments and diagnostic methods for a variety of diseases. He will return to Japan this summer to continue work on developing the program.

-Story by Christy Gordon, based on interview with Robert Makuch, January 29, 2004.

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