Susan T Mayne PhD

C.-E.A. Winslow Professor of Epidemiology (Chronic Diseases); Associate Director, Population Sciences at Yale Cancer Center; Department Chair, Chronic Disease Epidemiology

Research Interests

Nutritional epidemiology of chronic diseases; Nutrition and cancer prevention and survivorship; Cancer epidemiology and genetics

Current Projects

  • Novel, Noninvasive Biomarker of Fruit and Vegetable Intake
  • Epidemiology and Genetics of Early Onset Basal Cell Carcinoma
  • Epidemiologic Study of Esophageal/Gastric Adenocarcinoma (Barrett’s Esophagus and Adenocarcinoma International Consortium)

Research Summary

Professor Mayne's primary research interests are in the area of nutritional epidemiology of chronic diseases, and more specifically in nutrition and cancer prevention and survivorship. She is trained in nutritional biochemistry, epidemiology, and clinical trials, and has an interest in biomarkers of nutritional status. Professor Mayne's program of research has emphasized the role of dietary factors in the etiology of several major cancers. Her work involves both observational studies and intervention trials, with a particular emphasis on carotenoids. She also studies other lifestyle factors (e.g., tobacco, alcohol, tanning) and their interaction with diet and genetics in cancer risk.


Selected Publications

  • Mayne, S. T., Ferrucci, L., and Cartmel, B. Lessons learned from randomized clinical trials of micronutrient supplements for cancer prevention. Ann. Rev. Nutr. 2012 (in press).
  • Ferrucci, L. M., Cartmel, B., Molinaro, A. M., Leffell, D. J., Bale, A. E., and Mayne, S. T. Indoor tanning and risk of early-onset basal cell carcinoma. J. Am. Acad. Dermatol. 8 December 2011, doi: 10.1016/j.jaad.2011.11.940. NIHMS339428.
  • Manson, J. E., Mayne, S. T., Clinton, S. K. Vitamin D and prevention of cancer: Ready for prime time? N. Engl. J. Med. 364:1385-7, 2011[Epub ahead of print] doi: 10.1056/NEJMp1102022
  • Mayne, S. T., Cartmel, B., Scarmo, S., Lin, H., Leffell, D. J., Welch, E., Ermakov, I., Bhosale, P., Bernstein, P. S., and Gellermann, W. Non-invasive assessment of dermal carotenoids as a biomarker of fruit and vegetable intake. Am J Clin Nutr 2010 Aug 4. [Epub ahead of print] PMID: 20685953
  • Mayne, S. T., Cartmel, B., Kirsh, V. and Goodwin, W. J. Jr. Alcohol and tobacco use pre- and post-diagnosis, and survival in a cohort of patients with early stage cancers of the oral cavity, pharynx, and larynx. Cancer Epidemiol Biomark Prev 18:3368-3374, 2009. PMCID 2789339
  • Mayne, S. T., and Gruber, S. B. Emerging molecular technologies for identifying the risk of second cancers. Cancer Prev Res 2(7):605-607, 2009. PMCID 2733247
  • Kirsh, V.A., Peters, U., Mayne, S.T., Subar, A.F., Chatterjee, N., Johnson, C.C., and Hayes, B. on behalf of the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial. Prospective Study of Fruit and Vegetable Intake and Risk of Prostate Cancer. J Natl Cancer Inst 99:1200-1209, 2007.
  • Mayne, S.T. and Cartmel, B. Chemoprevention of Second Cancers. Cancer Epidemiology, Biomarkers and Prevention 15(11): 2033-2037, 2006.
  • Kirsh, V.A., Hayes, R.B., Mayne, S.T., Chatterjee, N., Subar, A.F., Dixon, L.B., Albanes, D., Andriole, G.L., Urban, D.A., and Peters, U. Supplemental and Dietary Vitamin E, ß-Carotene, and Vitamin C Intakes and Prostate Cancer Risk. Journal of the National Cancer Institute 98(4): 245-254, 2006.
  • Mayne, S.T., Risch, H.A., Dubrow, R., Chow, W-H., Gammon, M.D., Vaughan, T.L., Borchardt, L., Schoenbert, J.B., Stanford, J.L., West, A.B., Rotterdam, H., Blot, W.J., and Fraumeni, J.R., Jr. Carbonated Soft Drink Consumption and Risk of Esophageal Adenocarcinoma. Journal of the National Cancer Institute 98(1): 72-75, 2006.

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