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An HIV Vaccine By 2021? Here Is What Needs To Happen

Wait for it. Wait for it. That’s what the world has been doing ever since 1984 with the “it” being an effective and safe HIV vaccine. That year Margaret Heckler, then the U.S. Secretary of Health and Human Services, said in a press conference, “we hope to have a vaccine ready for testing in about two years,” and added, “"yet another terrible disease is about to yield to patience, persistence and outright genius.” Those words offered some encouragement that an HIV vaccine could have been available for use before the end of the 1980’s. Well, that prediction turned out to be off by oh about 30 years and counting. But after years of “wait for it,” there is optimism that the legendary arrival of a real HIV vaccine could happen as soon as 2021.

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  • A Zika Vaccine Could Virtually Eliminate Prenatal Infections

    A Zika vaccine could have a substantial effect on mitigating and preventing future Zika virus outbreaks. Through a combination of direct protection and indirect reduction of transmissions, virtual elimination is achievable, even with imperfect vaccine efficacy and coverage, a new Yale School of Public Health study finds.

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  • Saving lives efficiently across sectors: the need for a Congressional cost-effectiveness committee.

    In the preamble of the United States Constitution, a primary goal of government was established: “to promote the general Welfare”. Upon the opening of budget deliberations for the 115th US Congressional session, we suggest an evidence-based approach for the new Congress in aligning the budget process more closely with this national goal. In particular, we underscore the efficiency of the US public health sector in promoting societal welfare, and reveal a relative underinvestment in public health compared with other sectors.

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  • Fund global health: Save lives and money

    The White House budget, in both its 16 March and 23 May iterations, calls for substantial cuts to science and research. The Fogarty International Center of the National Institutes of Health is one of the many programs on the chopping block. Closing Fogarty, which has served as the cornerstone of the American strategy to promote global health, would be a mistake.

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  • Millions of New HIV Infections Can be Averted, YSPH Model Predicts

    Though there have been extraordinary advances in HIV/AIDS treatment in the past several years, the disease remains a serious health concern worldwide. Promising developments in HIV vaccines are occurring all the time, but their potential long-term impact is still unknown. Using a novel mathematical model, a team at the Yale School of Public Health predicts that vaccines used in concert with other interventions have the potential to avert several million cases of the disease in the coming years.

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