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Vaccines

Boy getting vaccination
credit: Dreamstime

Vaccines are one of the greatest achievements of public health in the 20th century. Universal immunization of infants and children, which began in the 1940s, has reduced the burden of previously common and potentially fatal infectious diseases. Despite remarkable progress, challenges remain. Each year, thousands of cases of vaccine preventable diseases still occur. Effective vaccines are still not available for many infectious diseases. Pathogens may evolve in response to vaccination with imperfect vaccines. Complacency toward immunization and anti-vaccination sentiment is growing in the United States and Europe while many vaccine preventable diseases persist in developing countries. Faculty work closely with public health practitioners and policymakers at CDC, WHO, the Bill and Melinda Gates Foundation, and GAVI on these issues.

Research in the Department of the Epidemiology of Microbial Diseases focuses on the following areas:

  • Development and use of novel mathematical and statistical models to predict and evaluate the impact of vaccinations 
  • Surveillance to monitor the impact of vaccines 
  • Evaluation of attitudes and barriers to vaccination 
  • Studies to optimize the effectiveness and cost-effectiveness of vaccination strategies 
  • Studies on the impacts of microbial evolution on long-term vaccine effectiveness 
  • Fundamental biological research on host immune effectors that will facilitate the development of new vaccines.

Relevant Courses

  • Immunology for Epidemiologists EMD 512 
  • Transmission Dynamic Models for Understanding Infectious Diseases EMD 553

Faculty of Interest

  • Assistant Professor of Epidemiology (Microbial Diseases)

    Research Interests
    Africa; Ecology; Genetics; Genetics, Population; Senegal; Malaria, Falciparum; Molecular Epidemiology; Malaria Vaccines; Disease Transmission, Infectious; Genomics; Host-Pathogen Interactions; Adaptive Immunity
  • Burnett and Stender Families Professor of Epidemiology (Microbial Diseases); Director of the Center for Infectious Disease Modeling and Analysis (CIDMA)

    Research Interests
    Acquired Immunodeficiency Syndrome; Africa, Southern; Ecology; Economics; Epidemiologic Methods; Epidemiology; Biological Evolution; HIV; Influenza, Human; Parasitology; Public Health; Tuberculosis; Global Health; Evolution, Planetary; Infectious Disease Medicine
  • Department Chair and Professor of Epidemiology (Microbial Diseases) and of Medicine (Infectious Diseases); Department Chair, Epidemiology of Microbial Diseases

    Research Interests
    Dengue; Epidemiology; Leptospirosis; Urban Health; Global Health; Meningitis, Bacterial; Infectious Disease Medicine
  • Professor of Epidemiology (Microbial Diseases); Director, Development Core at Center for Interdisciplinary Research on AIDS; Director, HPV Working Group at Yale; Co-Director, CT Emerging Infections Program at Yale

    Research Interests
    Epidemiologic Methods; Epidemiology; HIV; Sexually Transmitted Diseases; Vaccines; Communicable Diseases, Emerging; Qualitative Research; Human papillomavirus 11
  • Director, Yale Institute for Global Health; Associate Dean (Global Health Research), Yale School of Medicine; Professor of Medicine (Infectious Diseases), Yale School of Medicine; Susan Dwight Bliss Professor of Epidemiology of Microbial Diseases, Yale School of Public Health

  • Senior Associate Dean of Academic Affairs and Professor of Epidemiology (Microbial Diseases)

    Research Interests
    Drug Resistance; Pneumonia; Respiratory Tract Infections; Infection Control; Pulmonary Disease, Chronic Obstructive
  • Associate Professor of Epidemiology (Microbial Diseases)

    Research Interests
    Ecology; Immunization; Paratyphoid Fever; Rotavirus; Typhoid Fever; Global Health
  • Associate Professor of Epidemiology (Microbial Diseases)

    Research Interests
    Americas; Bacterial Infections; Biology; Carrier State; Communicable Disease Control; Denmark; Epidemiologic Methods; Europe; Fourier Analysis; Iceland; Influenza, Human; Netherlands; Population Characteristics; Public Health; Respiratory Tract Infections; Streptococcus pneumoniae; Diseases

Secondary & Adjunct Faculty

  • James Meek

    Associate Director School of Public Health and Lecturer in Epidemiology (Microbial Diseases); Associate Director, Yale Emerging Infections Program

    Research Interests
    Epidemiology; Tick Control; Ticks; Zoonoses
  • Eugene Shapiro

    Professor of Pediatrics (General Pediatrics) and of Epidemiology (Microbial Diseases); Vice Chair for Research, Department of Pediatrics; Deputy Director, Investigative Medicine PhD Program; Co-Director of Education, Yale Center for CLinical Investigation

    Research Interests
    Education; Lyme Disease; Investigative Techniques; Pediatrics; Vaccines; Case-Control Studies; Infectious Disease Medicine; Translational Medical Research
  • Kimberly Yousey-Hindes

    Epidemiologist 3 and Lecturer in Epidemiology (Microbial Diseases); Project Coordinator, FluSurv-NET, Connecticut Emerging Infections Program

    Research Interests
    Epidemiology; Influenza, Human; Lyme Disease; Population Surveillance; Rabies; Zoonoses; Infectious Disease Medicine

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