Nancy Ruddle, PhD

Professor Emeritus of and Senior Research Scientist in Epidemiology (Microbial Diseases)

Departments & Organizations

School of Public Health: Epidemiology of Microbial Diseases

Human and Translational Immunology Program

NIH T32 Program

Rheumatic Diseases Research Core

Status of Women in Medicine Committee (SWIM)

Vascular Biology and Therapeutics Program

Yale Cancer Center: Cancer Immunology


Nancy Ruddle is known for her discovery and analysis of lymphotoxin, a protein produced by T cells that plays a role in the protective immune system and destroys tumor cells. She and researchers in her laboratory have engaged in research on the lymphotoxin/tumor necrosis factor family, their regulation and roles in lymphoid organ development and pathogenesis of viral and autoimmune disease. The more than 170 scientific articles Ruddle has authored or co-authored have explored the immunology of such diseases as leukemia, experimental allergic encephalomyelitis and Leishmania amazonensis infection, among others. She continues to generate insight into the regulation and function of lymphoid organs through her analysis of the vessels crucial for their function.

Education & Training

PhD Yale University (1968)
BA Mount Holyoke College, Zoology (1962)
Postdoctoral Fellow Yale University

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Contact Info

Nancy Ruddle, PhD
Office Location
60 College Street, Rm 815
New Haven, CT 06510
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Mailing Address
Epidemiology of Microbial DiseasesPO Box 208034
60 College Street

New Haven, CT 06520-8034