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Heather Allore, PhD

Professor of Medicine (Geriatrics) and of Biostatistics; Leader, Data Management and Statistics Core, Yale Alzheimer's Disease Research Center, Internal Medicine; Co-director of the Biostatistics and Bioinformatics Core of the Yale Transdisciplinary Collaborative Center for Precision Medicine focused on Health Disparities; Adjunct Professor, Harldsplass Deaconess Hospital, University of Bergen, Norway

Contact Information

Heather Allore, PhD

Office Location

Mailing Address

  • Geriatrics

    300 George St Suite 775

    New Haven, CT, 06511

    United States

Appointments

Biography

The focus of my research collaborations and methodological development work as Director of Biostatistics at the Yale Program on Aging for 12 years and current Leader of the Yale Alzheimer's Disease Research Center's Data Management and Statistics Core. I founded the field of Gerontological Biostatistic. I lead the Design and Statistics Core of Imbedded Pragmatic Alzheimer’s Disease and AD-Related Dementias Clinical Trials Collaboratory. I am Co-director of the Biostatistics and Bioinformatics Core of the Yale Transdisciplinary Collaborative Center for Precision Medicine focused on Health Disparities, especially adults with multiple chronic conditions. I recently co-authored a paper on health disparities in the Decadal Survey of Behavioral and Social Science Research on Alzheimer’s Disease and Alzheimer’s Disease-Related Dementias. My innovated analytic methods include joint trajectories of cognition, function and mortality. Innovative designs and biostatistical methods are required to rigorously address the myriad of unanswered scientific questions related to older adults and persons with dementia, including risk prediction.

With over 200 peer-reviewed articles and continuous NIH funding since 2000, my research has focused on issues related to the design of clinical trials for and studies of older adults. These and other methodologic advances resulted in me being an invited speaker at an NIH/NIA conference on Longitudinal Methods and another on Clinical Trial Design. In 2017 and 2020, I co-chaired the Study Design and Metrics component of the NIH meeting on the 21st Century Cures Act: Inclusion Across the Lifespan I and II. I am Chair of the ADC Data Cores Steering Committee, member of the Executive Committee, and Co-Lead of the Data and Measures Committee of the NIA-funded AGING Initiative, which is a collaboration of Older Americans Independence Centers and the Healthcare Systems Research Network. I have a wealth of experience conducting epidemiologic studies and am a recognized authority on longitudinal statistical methods, including extended Cox models for state transitions, generalized estimating equations, mixed effects models, latent class trajectory models, and joint models. A defining hallmark of my biostatistical approach is that instead of developing analytic methods in the absence of a clinical question or adapting the study question to available analytical techniques, I adapt new statistical methods that suitably model the specific study question.

Education & Training

  • PhD
    Cornell University (1996)
  • MSc
    Cornell University (1993)
  • Postdoctoral Fellow
    Cornell University

Activities

  • Collaboration
    Amsterdam, Netherlands; Portland, United States; Ann Arbor, United States; Boston, United States; Providence, United States 2018
    Working with researchers on caregiving and alternatives to hospitalization for older adults
  • Sabbatical and Visiting Professor Research
    Christchurch, New Zealand; Sydney, Australia; Trondheim, Norway; Bergen, Norway (2017-2020)
    Worked with aging researchers
  • Sabbatical
    Sydney, Australia; Bergen, Norway (2016-2017)
  • Vice President
    Guilford, United States (2009-2014)
    Guilford Land Conservation Trust

Honors & Recognition

AwardAwarding OrganizationDate
FellowGerontological Society of America2016
Women’s Midcareer Leadership Competitive ApplicationAmerican Association of Medical Colleges2014
Paul Harris FellowRotary International2012
NRI Competitive Grants Postdoctoral Fellowship 96-35204-3441NRI Competitive Grants Postdoctoral Fellowship1996
Gamma Sigma Delta Research AwardGamma Sigma Delta, Honor Society1991
HR Anslie Leadership AwardCornell University1990

Professional Service

OrganizationRoleDate
NIHSpecial Emphasis Panel Reviewer, Support of Competitive Research (SCORE)2015 - Present
Gerontological Society of AmericaHealth Sciences Membership Committee2014 - 2017
NIH/NIAPPG P01Alzheimer’s Disease2014 - Present
Data Safety Monitoring BoardElectroencephalography Guidance of Anesthesia to Alleviate Geriatric Syndromes (ENGAGES) Study2014 - Present
NIH/NIAClinical Trial Advisory Panel2014 - Present
HMO Research Network/OAIC Aging InitiativeData and Measures Workgroup2014 - Present
NIH/NIASEP Review U19 DOMINANTLY INHERITED ALZHEIMER NETWORK2013
NIH/NIAIDSEP Reviewer, P01 Immunology, NIH/NIAID2011 - 2012
NIH/NIAIDSEP Immunology,2011 - 2012
Partnership for Anemia: Clinical and Translational TrialsData Safety Monitoring Board2010 - Present
Yale Center for Analytic ScienceYale Center for Analytic Science Executive Steering Committee2010 - Present
NIMHMember, Special Emphasis Panel, Treatment of Mental Illness2009 - 2010
Foundation for NIH review panel on SarcopeniaReview panel on Sarcopenia2009
Gerontological Society of AmericaConvener Gerontological Society of America Measures Statistics Research Design Section2008 - Present
CDCChair: CDC Special Emphasis Panel: Preparing People with Arthritis to Safely Select and Self Direct their Physical Activity2008 - Present
CDCCDC Mentored Public Health Research Scientist Development Award2007
NIH/NIANIH/NIA ASG Study Section2006 - 2012
Human Nutrition and Obesity Section USDA-NRICGPHuman Nutrition and Obesity Section USDA-NRICGP2006 - Present
USDA Small Business Initiative Grant ProgramUSDA Small Business Initiative Grant Program2003 - 2005
VA Cooperative Studies Program Coordinating CenterVA Cooperative Studies Program Coordinating Center Human Rights Committee2002 - Present

Departments & Organizations