Lei Yan, PhD

I am an Associate Research Scientist in Biostatistics at Yale Public Health.

My research focuses on the application of advanced causal inference methods to questions in comparative effectiveness research, utilizing large electronic health records and other observational data to enhance health decision-making. Ongoing projects include estimating the causal effects of pharmacotherapies on the short- and long-term risk of COVID-19, examining the use of antidepressants and their effects on individuals with major depression, evaluating the effectiveness of respiratory syncytial virus vaccines, assessing the efficacy and duration of dolutegravir-based regimens for individuals with HIV, and investigating gene-environment interactions in the development of childhood acute lymphoblastic leukemia. These projects are conducted collaboratively with faculty and researchers at Yale Public Health and the Clinical Epidemiology Research Center (CERC) at the VA Connecticut Healthcare System located in West Haven. My previous research focused on the financialization of commodity markets.