Dr Charalambous is the Deputy Chief Scientific Officer at The Aurum Institute. She is a South African trained medical doctor with a PhD in Epidemiology from the London School of Hygiene and Tropical Medicine. She has been involved in HIV program implementation since 1998, prior to antiretroviral therapy implementation, and was instrumental in the first large antiretroviral implementation project in the Anglo American companies in 2003 - 2007. She has been Principal Investigator of a number of cluster randomized and observational studies in issues of HIV and TB implementation and epidemiology in special populations. She has a special interest in TB and special populations such as miners, inmates, and TB contacts. She is the chair of the Monitoring and Evaluation working group of the South African National Department of Corrections Task Team and the co-chair of one of the working groups of the South African National TB Think Tank. She currently heads the Secretariat of the TB Think Tank. She has supported and supervised a number of foreign-based and local students throughout the years.