- April 12, 2024Source: Cancer Therapy Advisor
Does Fracking Cause Cancer?
- March 04, 2024Source: Newsweek
Woman Who Worked Out 5 Times A Week Shocked After Finding Lump
- February 06, 2024Source: CNN
Dr. Megan Ranney on King Charles' Cancer Diagnosis and the Importance of Regular Screenings
- February 06, 2024Source: CGTN America
Dr. Chen Xi Discusses Sharp Rise in Cancer Cases
Cancer
More people today die from cancer than from almost any other cause in the world. The challenges posed by cancer are immense and top scientists at the Yale School of Public Health are committed to reducing its toll.
The departments of Chronic Disease Epidemiology, Biostatistics and Health Policy and Management are heavily focused on a wide variety of cancer-related research, and the Department of Environmental Health Sciences is renowned for novel approaches to the study of how environmental exposures affect health outcomes. From key partnerships with the Yale Cancer Center to collaborative efforts locally and globally, YSPH scientists are taking significant steps toward preventing and treating a wide range of cancers. Today, research in cancer and other chronic diseases encompasses interdisciplinary teams committed to understanding cancer causation and etiology, prevention, screening and early detection, risk factors, environmental exposures, social determinants of health and survival.
A variety of technologies and approaches are used to detect mechanisms and characteristics of the many different types of cancer, including genomics, metabolomics, social and behavioral effects, evolutionary biology, biostatistical methodology and study design, and outcomes research.
The Yale School of Public Health maintains biospecimens and data from thousands of individuals in more than a dozen studies that can be made applied to future research. It also has partnerships with numerous international cancer researchers, and is the home of leading experts in clinical trial design and data management, and genomic and metabolic centers.
Recent Publications
2024
- Estimation of multiple networks with common structures in heterogeneous subgroups.Qin X, Hu J, Ma S, Wu M. J Multivar Anal. 2024 Jul; 2024 Feb 13. PMID: 38433779.
- Dietary intake of vitamin C and gastric cancer: a pooled analysis within the Stomach cancer Pooling (StoP) Project.Sassano M, Seyyedsalehi MS, Collatuzzo G, Pelucchi C, Bonzi R, Ferraroni M, Palli D, Yu GP, Zhang ZF, López-Carrillo L, Lunet N, Morais S, Zaridze D, Maximovich D, Martín V, Castano-Vinyals G, Vioque J, González-Palacios S, Ward MH, Malekzadeh R, Pakseresht M, Hernández-Ramirez RU, López-Cervantes M, Negri E, Turati F, Rabkin CS, Tsugane S, Hidaka A, Lagiou A, Lagiou P, Camargo MC, Curado MP, Boccia S, La Vecchia C, Boffetta P. Gastric Cancer. 2024 May; 2024 Mar 4. PMID: 38436761.
- Endocrine disrupting chemical mixture exposure and risk of papillary thyroid cancer in U.S. military personnel: A nested case-control study.Denic-Roberts H, McAdam J, Sjodin A, Davis M, Jones R, Ward MH, Hoang TD, Ma S, Zhang Y, Rusiecki JA. Sci Total Environ. 2024 Apr 20; 2024 Feb 28. PMID: 38428594.
- DNA methylation-based telomere length is associated with HIV infection, physical frailty, cancer, and all-cause mortality.Liang X, Aouizerat BE, So-Armah K, Cohen MH, Marconi VC, Xu K, Justice AC. Aging Cell. 2024 Apr 17; 2024 Apr 17. PMID: 38629454.
- Immunotherapy utilization patterns in patients with advanced cancer and autoimmune disease.Li H, Huntington S, Gross C, Wang SY. PLoS One. 2024; 2024 Apr 16. PMID: 38625861.
- U.S. Women with Invasive Cervical Cancer: Characteristics and Potential Barriers to Prevention.Rosenblum HG, Gargano JW, Cleveland AA, Dahl RM, Park IU, Whitney E, Castilho JL, Sackey E, Niccolai LM, Brackney M, Debess E, Ehlers S, Bennett NM, Kurtz R, Unger ER, Markowitz LE. J Womens Health (Larchmt). 2024 Apr 12; 2024 Apr 12. PMID: 38608239.
- A supervised bayesian factor model for the identification of multi-omics signatures.Gygi JP, Konstorum A, Pawar S, Aron E, Kleinstein SH, Guan L. Bioinformatics. 2024 Apr 11; 2024 Apr 11. PMID: 38603606.
- A noncoding regulatory variant in IKZF1 increases acute lymphoblastic leukemia risk in Hispanic/Latino children.de Smith AJ, Wahlster L, Jeon S, Kachuri L, Black S, Langie J, Cato LD, Nakatsuka N, Chan TF, Xia G, Mazumder S, Yang W, Gazal S, Eng C, Hu D, Burchard EG, Ziv E, Metayer C, Mancuso N, Yang JJ, Ma X, Wiemels JL, Yu F, Chiang CWK, Sankaran VG. Cell Genom. 2024 Apr 10; 2024 Mar 26. PMID: 38537633.
- Long-term exposure to ambient fine particulate matter and risk of liver cancer in the NIH-AARP Diet and Health Study.Ma X, Fisher JA, McGlynn KA, Liao LM, Vasiliou V, Sun N, Kaufman JD, Silverman DT, Jones RR. Environ Int. 2024 Apr 5; 2024 Apr 5. PMID: 38636274.
- Characterization of accelerated approval status, trial endpoints and results, and recommendations in guidelines for oncology drug treatments from the National Comprehensive Cancer Network: cross sectional study.Mooghali M, Mitchell AP, Skydel JJ, Ross JS, Wallach JD, Ramachandran R. BMJ Med. 2024; 2024 Apr 5. PMID: 38596814.
- Anatomical distribution of melanoma and non-melanoma skin cancer according to auricular subunits and gender: A single-centre retrospective analysis.Crisan D, Schneider LA, Kastler S, Scharffetter-Kochanek K, Crisan M, Radu C, Strilciuc S. Indian J Dermatol Venereol Leprol. 2024 Apr 4; 2024 Apr 4. PMID: 38594976.
- Study protocol for the implementation of Centering Patients with Fibroids, a novel group education and empowerment program for patients with symptomatic uterine fibroids.Noel NL, Abrams J, Mudafort ER, Babu A, Forbes E, Hill L, Hill CC, Valbrun TG, Osian N, Wise LA, Kuohung W. Reprod Health. 2024 Apr 1; 2024 Apr 1. PMID: 38561795.
- Nitrate exposure from drinking water and dietary sources among Iowa farmers using private wells.Skalaban TG, Thompson DA, Madrigal JM, Blount BC, Espinosa MM, Kolpin DW, Deziel NC, Jones RR, Beane Freeman L, Hofmann JN, Ward MH. Sci Total Environ. 2024 Apr 1; 2024 Feb 11. PMID: 38350573.
- Hierarchical False Discovery Rate Control for High-dimensional Survival Analysis with Interactions.Liang W, Zhang Q, Ma S. Comput Stat Data Anal. 2024 Apr; 2023 Dec 5. PMID: 38098875.
- Effect of a Personalized Tobacco Treatment Intervention on Smoking Abstinence in Individuals Eligible for Lung Cancer Screening.Cartmel B, Fucito LM, Bold KW, Neveu S, Li F, Rojewski AM, Gueorguieva R, O'Malley SS, Herbst RS, Toll BA. J Thorac Oncol. 2024 Apr; 2023 Nov 15. PMID: 37977486.
- Information-incorporated sparse hierarchical cancer heterogeneity analysis.Han W, Zhang S, Ma S, Ren M. Stat Med. 2024 Mar 30; 2024 Mar 30. PMID: 38553996.
- Detection of hepatocellular carcinoma methylation markers in salivary DNA.Mezzacappa C, Wang Z, Lu L, Risch H, Taddei T, Yu H. Biosci Rep. 2024 Mar 29. PMID: 38457142.
- Threats to social safety and neuro-inflammatory mechanisms underlying sexual orientation disparities in depression symptom severity: A prospective cohort study of young adults.Bränström R, Hatzenbuehler ML, Lattanner MR, Hollinsaid NL, McDade TW, Pachankis JE. Brain Behav Immun. 2024 Mar 27; 2024 Mar 27. PMID: 38548185.
- Hypertension and risk of endometrial cancer: a pooled analysis in the Epidemiology of Endometrial Cancer Consortium (E2C2).Habeshian TS, Peeri NC, De Vivo I, Schouten LJ, Shu XO, Cote ML, Bertrand KA, Chen Y, Clarke MA, Clendenen TV, Cook LS, Costas L, Dal Maso L, Freudenheim JL, Friedenreich CM, Gallagher G, Gierach GL, Goodman MT, Jordan SJ, La Vecchia C, Lacey JV, Levi F, Liao LM, Lipworth L, Lu L, Matías-Guiu X, Moysich KB, Mutter GL, Na R, Naduparambil J, Negri E, O'Connell K, O'Mara TA, Onieva Hernández I, Palmer JR, Parazzini F, Patel AV, Penney KL, Prizment AE, Ricceri F, Risch HA, Sacerdote C, Sandin S, Stolzenberg-Solomon RZ, van den Brandt PA, Webb PM, Wentzensen N, Wijayabahu AT, Wilkens LR, Xu W, Yu H, Zeleniuch-Jacquotte A, Zheng W, Du M, Setiawan VW. Cancer Epidemiol Biomarkers Prev. 2024 Mar 26; 2024 Mar 26. PMID: 38530242.
- Artificial intelligence-enhanced risk stratification of cancer therapeutics-related cardiac dysfunction using electrocardiographic images.Oikonomou EK, Sangha V, Dhingra LS, Aminorroaya A, Coppi A, Krumholz HM, Baldassarre LA, Khera R. medRxiv. 2024 Mar 19; 2024 Mar 19. PMID: 38562897.
- Organochlorine pesticides and risk of papillary thyroid cancer in U.S. military personnel: a nested case-control study.Rusiecki JA, McAdam J, Denic-Roberts H, Sjodin A, Davis M, Jones R, Hoang TD, Ward MH, Ma S, Zhang Y. Environ Health. 2024 Mar 19; 2024 Mar 19. PMID: 38504322.
- Improving lifestyle behaviors during chemotherapy for breast cancer: The Lifestyle, Exercise, and Nutrition Early After Diagnosis (LEANer) Trial.Puklin LS, Ferrucci LM, Harrigan M, McGowan C, Zupa M, Cartmel B, Li FY, Ligibel JA, Spiegelman D, Sharifi M, Sanft T, Irwin ML. Cancer. 2024 Mar 12; 2024 Mar 12. PMID: 38470431.
- Inflammation, endothelial injury, and the acute respiratory distress syndrome after out-of-hospital cardiac arrest.Katsandres SC, Hall J, Danielson K, Sakr S, Dean SG, Carlbom DJ, Wurfel MM, Bhatraju PK, Hippensteel JA, Schmidt EP, Oshima K, Counts CR, Sayre MR, Henning DJ, Johnson NJ. Resusc Plus. 2024 Mar; 2024 Mar 5. PMID: 38463638.
- Conceptualization and Assessment of 24-H Timing of Eating and Energy Intake: A Methodological Systematic Review of the Chronic Disease Literature.O'Connor SG, O'Connor LE, Higgins KA, Bell BM, Krueger ES, Rawal R, Hartmuller R, Reedy J, Shams-White MM. Adv Nutr. 2024 Mar; 2024 Jan 18. PMID: 38242444.
- Grow502: Centering Community in Medical Education via a Student-Created Organization Focused on Cultivating a Healthy Community.Udoh MO, Mian Z, Anakwenze L, Okeke C, Ziegler C, Sawning S. Health Promot Pract. 2024 Mar; 2022 Dec 13. PMID: 36511091.
Centers and other resources
- Yale Cancer Center (YCC)The Center provides the best approaches for the prevention, detection, diagnosis, and treatment of cancer.
- Yale Center for Analytical Sciences (YCAS)YCAS collaborative team provides expertise in the design, conduct, and analysis of health and health care studies, methodological development, and education and training.
- Yale-Griffin Prevention Research Center (PRC)The PRC works with community partners to develop and implement community-based approaches to prevent and control chronic diseases such as heart disease, diabetes, and cancer.