Parental Birth Abnormalities and Offspring’s Autism Linked
In a study of medical registry records of nearly 400,000 parent-child pairs from Denmark, a Yale School of Public Health study found that parents who themselves born very prematurely are nearly twice as likely to have children with autism spectrum disorder.
Jawless Lamprey Takes a Bite out of Oncogene Evolution
By carefully tracing the evolution of a select number of cancer-causing genes in a variety of species, the researchers evaluated which animals are — and are not — effective in gauging how an analogue of those genes in humans can lead to cancer. What they found is surprising: jawless fish such as lampreys share significant similarities in these certain genes compared to humans, while fruit flies do not.
Yale Launches Comprehensive DNA Sequencing Project, With Aim of Predicting, Preventing, and Treating Gene-related Diseases
Generations, a collaboration between Yale School of Medicine and Yale New Haven Health System, is one of the largest DNA sequencing projects of its kind in the United States.
Women’s Health Research at Yale funds studies on pain relief, cannabis, and genetic origins of sex differences in disease
Women’s Health Research at Yale (WHRY) today announced funding for first-of-their-kind studies on pain relief, cannabis, and the genetic basis of sex differences across a broad range of ailments, including Alzheimer’s disease and heart disease.
Yale Study Identifies How Cancer Drug Inhibits DNA Repair in Cancer Cells
Yale Cancer Center researchers have found that a cancer drug thought to be of limited use possesses an unforeseen property. It is able to stop certain cancer cells from repairing their DNA in order to survive. The study suggests that combining this drug, cediranib, with other agents could potentially deliver a lethal blow in cancer that uses a specific process to create DNA repair cells.
Novel YSPH Framework Helps Identify Genes Associated with Disease
A powerful analytical tool, known as UTMOST, developed by Hongyu Zhao, Ph.D., the Ira V. Hiscock Professor of Biostatistics at the Yale School of Public Health, and colleagues could allow researchers to design therapeutic drugs that more effectively combat disease.
Happy in Marriage? Genetics May Play a Role
People fall in love for many reasons — similar interests, physical attraction, and shared values among them. But if they marry and stay together, their long-term happiness may depend on their individual genes or those of their spouse, says a new study led by Yale School of Public Health researchers.
Ellen Kan of the Yale Daily News interviews Jeffrey Townsend about the new Center
n our first podcast, Ellen Kan, staff reporter at the Yale Daily News, interviews Jeffrey Townsend about the new Center for Genetically Encoded Materials. We cover what the Center is, what it will be doing, and what technologies it could lead to. This interview was recorded on the 19th of September, 2017.Source: Yale Podcast Network
Uncovering Asthma's Genetic Origins
The statistics about asthma are staggering. According to a recent Global Burden of Disease Study, more than 334 million people worldwide may suffer from this common chronic disease. In the United States, the Centers for Disease Control and Prevention reports that asthma afflicts an estimated 25 million people, about 8 percent of the population.
Yale scientists develop novel genetic analysis model
After almost a decade of research, Yale scientists in partnership with scientists from Howard University have published a new genetic analysis tool that may soon change the way we differentiate between humans and chimpanzees, our close genetic relatives.Source: Yale Daily News
Yale Study: Minority Breast Cancer Patients Less Likely To Have Genetic Test
A genetic test that helps doctors determine how best to treat breast cancer—and whether chemotherapy is likely to help—is significantly more likely to be administered to white women than blacks or Hispanics, a Yale study has found.Source: Connecticut Health I-Team
Yale study reveals unequal access to breast cancer test
Gene expression profiling is an emerging technology for identifying genes whose activity may be helpful in assessing disease prognosis and guiding therapy. In recent years, gene expression profiling has been successfully used in breast cancer research, according to the federal government. Gene expression profiling substantially impacts treatment decision-making by determining which female breast cancer patients might—or might not—respond to particular treatment options. Although the tests are readily available, Yale Cancer Center researchers have found that white women with breast cancer are far more likely to receive a particular test than black or Hispanic women with the same diagnosis.Source: Life Science Daily
Tanning Dependence Linked to Other Addictive Behaviors, New Study Finds
Despite the known dangers of exposure to ultraviolet light, many people continue to sunbathe and use indoor tanning beds with some users exhibiting a dependence to tanning. A new study from the Yale School of Public Health finds that such dependence is also associated with other addictive behaviors.
The promise of precision medicine for rheumatoid arthritis
In a new study, a Yale-led research team identified the mechanism of a gene that raises the risk of severe rheumatoid arthritis in susceptible individuals. The finding may lead to the development of treatment based on the genetic profiles of arthritis patients, the researchers said.