Infectious Diseases
Laboratory Science
The Department of Epidemiology of Microbial Diseases has an established record of public health discovery through laboratory science. In the school’s first century, YSPH led the fight against poliomyelitis, housed the Arbovirus Research Unit which moved from the Rockefeller Foundation to Yale in 1964 (and was home to Nobel prize-winning scientist Max Theiler and other prominent scientists), as well as the WHO serum bank. Today, Yale is home to several modern laboratories that address vector-borne diseases transmitted by tsetse flies, ticks, mosquitoes and sand flies. In addition, our scientists are pursuing solutions to respiratory ailments, antibiotic resistance, diagnostic testing, vaccine development and infections related to STIs and intravenous drug use.
Recent Publications
2024
- Factors influencing adverse events following COVID-19 vaccination.Villanueva P, McDonald E, Croda J, Croda MG, Dalcolmo M, Dos Santos G, Jardim B, Lacerda M, Lynn DJ, Marshall H, Oliveira RD, Rocha J, Sawka A, Val F, Pittet LF, Messina NL, Curtis N. Hum Vaccin Immunother. 2024 Dec 31; 2024 Mar 6. PMID: 38445666.
- A scoping review of active, participant centred, digital adverse events following immunization (AEFI) surveillance of WHO approved COVID-19 vaccines: A Canadian immunization Research Network study.Serhan M, Psihogios A, Kabir N, Bota AB, Mithani SS, Smith DP, Zhu DT, Greyson D, Wilson S, Fell D, Top KA, Bettinger JA, Wilson K. Hum Vaccin Immunother. 2024 Dec 31; 2024 Feb 19. PMID: 38374618.
- Sociodemographic correlates of late HIV diagnosis among men who have sex with men (MSM) in Ghana.Aidoo-Frimpong G, Tong G, Akyirem S, Abwoye DN, Nwanaji-Enwerem U, López DJ, Wilton L, Nelson LE. AIDS Care. 2024 Jun; 2024 Mar 9. PMID: 38460152.
- An update on clinical presentation and responses to therapy of patients with hereditary hypophosphatemic rickets with hypercalciuria (HHRH).Zhu Z, Bo-Ran Ho B, Chen A, Amrhein J, Apetrei A, Carpenter TO, Lazaretti-Castro M, Colazo JM, McCrystal Dahir K, Geßner M, Gurevich E, Heier CA, Simmons JH, Hunley TE, Hoppe B, Jacobsen C, Kouri A, Ma N, Majumdar S, Molin A, Nokoff N, Ott SM, Peña HG, Santos F, Tebben P, Topor LS, Deng Y, Bergwitz C. Kidney Int. 2024 May; 2024 Feb 15. PMID: 38364990.
- Using Data-To-Care Strategies to Optimize the HIV Care Continuum in Connecticut: Results From a Randomized Controlled Trial.Machavariani E, Miceli J, Altice FL, Fanfair RN, Speers S, Nichols L, Jenkins H, Villanueva M. J Acquir Immune Defic Syndr. 2024 May 1. PMID: 38324241.
- Social support as a mediator between mental health and stigma among newly HIV-positive men who have sex with men.Zhao Y, Khoshnood K, Sheng Y. Int J STD AIDS. 2024 May; 2024 Feb 5. PMID: 38314565.
- Digital Interventions to Support Lung Cancer Screening: A Systematic Review.Odole IP, Andersen M, Richman IB. Am J Prev Med. 2024 May; 2024 Jan 20. PMID: 38246408.
- Long COVID Characteristics and Experience: A Descriptive Study from the Yale LISTEN Research Cohort.Sawano M, Wu Y, Shah RM, Zhou T, Arun AS, Khosla P, Kaleem S, Vashist A, Bhattacharjee B, Ding Q, Lu Y, Caraballo C, Warner F, Huang C, Herrin J, Putrino D, Michelsen T, Fisher L, Adinig C, Iwasaki A, Krumholz HM. Am J Med. 2024 Apr 23; 2024 Apr 23. PMID: 38663793.
- Factors Associated with Long COVID Recovery among US Adults.Shah KM, Shah RM, Sawano M, Wu Y, Bishop P, Iwasaki A, Krumholz HM. Am J Med. 2024 Apr 20; 2024 Apr 20. PMID: 38649004.
- Feasibility and utility of a combined nasogastric-tube-and-string-test device for bacteriologic confirmation of pulmonary tuberculosis in young children.Khambati N, Song R, Smith JP, Bijker EM, McCarthy K, Click ES, Mchembere W, Okumu A, Musau S, Okeyo E, Perez-Velez CM, Cain K. Diagn Microbiol Infect Dis. 2024 Apr 18; 2024 Apr 18. PMID: 38657352.
- Host-microbe multiomic profiling reveals age-dependent immune dysregulation associated with COVID-19 immunopathology.Phan HV, Tsitsiklis A, Maguire CP, Haddad EK, Becker PM, Kim-Schulze S, Lee B, Chen J, Hoch A, Pickering H, van Zalm P, Altman MC, Augustine AD, Calfee CS, Bosinger S, Cairns CB, Eckalbar W, Guan L, Jayavelu ND, Kleinstein SH, Krammer F, Maecker HT, Ozonoff A, Peters B, Rouphael N, Montgomery RR, Reed E, Schaenman J, Steen H, Levy O, Diray-Arce J, Langelier CR. Sci Transl Med. 2024 Apr 17; 2024 Apr 17. PMID: 38630846.
- DNA methylation-based telomere length is associated with HIV infection, physical frailty, cancer, and all-cause mortality.Liang X, Aouizerat BE, So-Armah K, Cohen MH, Marconi VC, Xu K, Justice AC. Aging Cell. 2024 Apr 17; 2024 Apr 17. PMID: 38629454.
- Air pollution changes due to COVID-19 lockdowns and attributable mortality changes in four countries.Ma Y, Nobile F, Marb A, Dubrow R, Kinney PL, Peters A, Stafoggia M, Breitner S, Chen K. Environ Int. 2024 Apr 16; 2024 Apr 16. PMID: 38640613.
- A supervised bayesian factor model for the identification of multi-omics signatures.Gygi JP, Konstorum A, Pawar S, Aron E, Kleinstein SH, Guan L. Bioinformatics. 2024 Apr 11; 2024 Apr 11. PMID: 38603606.
- Identifying trusted local sources and predicting behavior change pathways according to COVID-19 vaccination status: Results of a 2022 statewide survey of Alaskan adults.Cameron DB, Grage L, Van Wyck R, Edwards A, Chavez Mapaye J, Cheng A, Garcia G. Vaccine. 2024 Apr 11; 2024 Mar 14. PMID: 38490821.
- Effectiveness of a bivalent mRNA vaccine dose against symptomatic SARS-CoV-2 infection among U.S. Healthcare personnel, September 2022-May 2023.Plumb ID, Briggs Hagen M, Wiegand R, Dumyati G, Myers C, Harland KK, Krishnadasan A, James Gist J, Abedi G, Fleming-Dutra KE, Chea N, Lee JE, Kellogg M, Edmundson A, Britton A, Wilson LE, Lovett SA, Ocampo V, Markus TM, Smithline HA, Hou PC, Lee LC, Mower W, Rwamwejo F, Steele MT, Lim SC, Schrading WA, Chinnock B, Beiser DG, Faine B, Haran JP, Nandi U, Chipman AK, LoVecchio F, Eucker S, Femling J, Fuller M, Rothman RE, Curlin ME, Talan DA, Mohr NM. Vaccine. 2024 Apr 11; 2023 Nov 14. PMID: 37973512.
- HIV-1-infected T cell clones are shared across cerebrospinal fluid and blood during ART.Wang M, Yoon J, Reisert H, Das B, Orlinick B, Chiarella J, Halvas EK, Mellors J, Pang AP, Barakat LA, Fikrig M, Cyktor J, Kluger Y, Spudich S, Corley MJ, Farhadian SF. JCI Insight. 2024 Apr 8; 2024 Apr 8. PMID: 38587074.
- Exploring Attitudes Toward Pre-Exposure Prophylaxis for HIV Prevention Prior to Implementation Among Female Sex Workers in Malaysia: Results from a Qualitative Study.Foley S, Keene DE, Shrestha R, Brown SE, Gautam K, Sutherland RA, Maviglia F, Saifi R, Wickersham JA. Patient Prefer Adherence. 2024; 2024 Apr 5. PMID: 38595805.
- The recent rapid expansion of multidrug resistant Ural lineage Mycobacterium tuberculosis in Moldova.Chitwood MH, Colijn C, Yang C, Crudu V, Ciobanu N, Codreanu A, Kim J, Rancu I, Rhee K, Cohen T, Sobkowiak B. Nat Commun. 2024 Apr 5; 2024 Apr 5. PMID: 38580642.
- Combined Motivational Interviewing and Ecological Momentary Intervention to Reduce Hazardous Alcohol Use Among Sexual Minority Cisgender Men and Transgender Individuals: Protocol for a Randomized Controlled Trial.Lauckner C, Takenaka BP, Sesenu F, Brown JS, Kirklewski SJ, Nicholson E, Haney K, Adatorwovor R, Boyd DT, Fallin-Bennett K, Restar AJ, Kershaw T. JMIR Res Protoc. 2024 Apr 5; 2024 Apr 5. PMID: 38578673.
- "We Take Care of Our Young, No Matter What," Experiences of Engagement in HIV Care Among Black Mothers Parenting Dependent Children in Southwestern Pennsylvania: A Retrospective Descriptive Qualitative Study.Mangum LC, Aidoo-Frimpong G, Alexander I, Waddell A, Whitfield DL. J Assoc Nurses AIDS Care. 2024 Apr 4; 2024 Apr 4. PMID: 38574350.
- Identifying signs and symptoms of urinary tract infection from emergency department clinical notes using large language models.Iscoe M, Socrates V, Gilson A, Chi L, Li H, Huang T, Kearns T, Perkins R, Khandjian L, Taylor RA. Acad Emerg Med. 2024 Apr 3; 2024 Apr 3. PMID: 38567658.
- IgG Isotypes Targeting a Recombinant Chimeric Protein of Trypanosoma cruzi in Different Clinical Presentations of Chronic Chagas Disease.Serrano IM, Ribeiro G, Santos RS, Cruz JS, Lanza FC, Santos EFD, Almeida MC, Soares JFS, Luquetti AO, Celedon PAF, Zanchin NIT, Santos FLN, Reis MGD. Am J Trop Med Hyg. 2024 Apr 3; 2024 Feb 27. PMID: 38412539.
- Disparities in Tuberculosis Incidence by Race and Ethnicity Among the U.S.-Born Population in the United States, 2011 to 2021 : An Analysis of National Disease Registry Data.Li Y, Regan M, Swartwood NA, Barham T, Beeler Asay GR, Cohen T, Hill AN, Horsburgh CR Jr, Khan A, Marks SM, Myles RL, Salomon JA, Self JL, Menzies NA. Ann Intern Med. 2024 Apr; 2024 Apr 2. PMID: 38560914.
- Identifying local foci of tuberculosis transmission in Moldova using a spatial multinomial logistic regression model.Lan Y, Crudu V, Ciobanu N, Codreanu A, Chitwood MH, Sobkowiak B, Warren JL, Cohen T. EBioMedicine. 2024 Apr; 2024 Mar 26. PMID: 38531172.