Nathan Grubaugh, PhD

Assistant Professor

Departments & Organizations

School of Public Health: Epidemiology of Microbial Diseases | YSPH Global Health Concentration

Center for RNA Science and Medicine

Yale Institute for Global Health


Nathan Grubaugh joined the faculty at Yale School of Public Health in 2018. Before going to graduate school, he spent ~7 years working in the biotech industry doing toxicology studies, monitoring food production lines for pathogens, and developing early phase vaccine candidates. He earned his MS in biotechnology from Johns Hopkins University (2011) while conducting research at the NIH and the US Army Research Institute of Infectious Diseases (focus on mosquito-borne virus surveillance). Dr. Grubaugh earned his PhD in microbiology from Colorado State University in 2016 (focus on West Nile virus evolution), and went on to be a postdoctoral fellow at The Scripps Research Institute to study the 2015-2017 Zika virus epidemic. Building on these experiences, the Grubaugh Lab uses genomics to determine the emergence risk and to track the spread of mosquito-borne viruses, like Zika, chikungunya, dengue, and West Nile. Specifically, the lab 1) sequences viruses during outbreaks for epidemiological investigations (genomic epidemiology), 2) determines the disease phenotype and transmission fitness of novel virus mutations that occur during outbreaks (functional genomics), and 3) maps the evolutionary pathways that a virus may take to adapt to a new environment (experimental evolution). To do these studies, which include expertise in field work, computational biology, and laboratory experimentation, the Grubaugh Lab is building a diverse team and collaborates with many groups from around the world. Their goals are to integrate genomic data into surveillance and response programs to better prevent and control future mosquito-borne virus outbreaks. Read more about their work at

Education & Training

PhD Colorado State University, Microbiology (2016)
MS Johns Hopkins University, Biotechnology (2011)
BS Western Michigan University, Biomedical Sciences (2005)
Postdoctoral Fellow The Scripps Research Institute

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Contact Info

Nathan Grubaugh, PhD
Lab Location
LEPH 60760 College Street
New Haven, CT 06510
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Office Location
LEPH 60860 College Street
New Haven, CT 06510
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Mailing Address
60 College St
LEPH 608

New Haven, CT 06510

Grubuagh Lab

Research Image 1

The Grubaugh Lab uses genomics to investigate how mosquito-borne viruses, like Zika, dengue, and chikungunya, spread (genomic epidemiology), cause disease (functional evolution), and adapt to new environments (experimental evolution).